Defects in chromatin modifiers and remodelers have been described both for hematological and solid malignancies, corroborating and strengthening the role of epigenetic aberrations in the etiology of cancer.Furthermore, epigenetic marks-DNA methylation, histone modifications, chromatin remodeling, and microRNA-can be considered potential markers of
BackgroundThe reservoir and mode of transmission of Mycobacterium ulcerans, the causative agent of Buruli ulcer, remain unknown.Ecological, genetic and epidemiological information nonetheless suggests that M.ulcerans may reside in aquatic protozoa.Methodology/principal findingsWe experimentally infected Acanthamoeba polyphaga with M.ulcerans and fo
Maritime patrols are necessary because Indonesia is vulnerable to maritime threats and disturbances.Patrols are not optimally covered the sea and the regulations are not comprehensive to be synergy guidelines.This article discusses how to synergize effective and efficient patrols at the six maritime security Sports Posters institutions, and finally